Life Science Data Analysis Problem Solving

Keigo YAMAKITA
山北 啓吾

Department of Biology, Graduate School of Science and Engineering, Chiba University, Japan

I study how chromatin structure relates to genome stability, using bioinformatics to read it out of sequencing data. Combining wet-lab experiments with large-scale data analysis, I am building an ATAC-seq–based framework to assess the non-genotoxic effects of chemicals on the genome.
The portrait is AI-generated (the dogs on my shoulders are my own).

Keigo Yamakita
About

Background

Summary

After graduating from the Faculty of Science at Chiba University, I am now a master's student in the same university's graduate school, working on chromatin metabolism. To quantitatively evaluate how chemicals and gene mutations affect chromatin structure and genome stability, I develop next-generation sequencing workflows and evaluation methods centered on ATAC-seq. By combining wet-lab experiments with bioinformatic analysis of large datasets, I aim to clarify how epigenomic changes influence innate immune responses and cancer risk.

Research Interests

Epigenomics · Chromatin accessibility
Genome stability · Bioinformatics

Degree

Master's program (in progress)

Publications & Presentations

Journal articles and conference presentations (including co-authored). Titles of presentations given in Japanese are translated.

Journal Articles

2025 · 📄 Journal Article
Dual-directional epi-genotoxicity assay for assessing chemically induced epigenetic effects utilizing the housekeeping TK gene
Haruto Yamada, Mizuki Odagiri, Keigo YAMAKITA, et al. · Scientific Reports 15, 7780 (2025)
EpigenomeGenotoxicityTK gene
doi:10.1038/s41598-025-92121-6 →

Conference Presentations

Research overview: assessing chromatin structure with ATAC-seq (in Japanese) →

Awards

Society awards and honors

Contact

Feel free to get in touch.